component C1

By Targets:	Antibiotic (1) Bacterial (1) Complement System (2) Endogenous Metabolite (3) Isotope-Labeled Compounds (1) Nucleoside Antimetabolite/Analog (1)
By Research Areas:	Cardiovascular Disease (2) Infection (1) Inflammation/Immunology (2) Metabolic Disease (2) Neurological Disease (1)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-148286

Gentamicin C1a	Antibiotic Bacterial	Infection
Gentamicin C1a is the precursor of the semi-synthetic antibiotic Etimicin, and has antibacterial activity. Gentamicin C1a is the major component of the Gentamicin complex .

HY-P99050

Sutimlimab	Complement System	Cardiovascular Disease Inflammation/Immunology
Sutimlimab, a first-in-class complement protein component 1, s subcomponent (C1s) inhibitor, can be used for the research of cold agglutinin disease. C1s is a serine protease which cleaves C4 and C2 to form the C3 convertase .

HY-W371164

C1s-IN-1

Complement System Inflammation/Immunology

C1s-IN-1 (compound A1) is a selective and competitive inhibitor of C1s. C1s-IN-1 binds directly to C1s with a K_d of 9.8 μM .

C1s-IN-1	Complement System	Inflammation/Immunology
C1s-IN-1 (compound A1) is a selective and competitive inhibitor of C1s. C1s-IN-1 binds directly to C1s with a K_d of 9.8 μM .

HY-B0158S2

Cytidine-13C-1 Cytosine β-D-riboside-¹³C-1; Cytosine-1-β-D-ribofuranoside-¹³C-1	Isotope-Labeled Compounds Endogenous Metabolite Nucleoside Antimetabolite/Analog	Neurological Disease
Cytidine- ¹³C-1 is the ¹³C labeled Cytidine. Cytidine is a pyrimidine nucleoside and acts as a component of RNA. Cytidine is a precursor of uridine. Cytidine controls neuronal-glial glutamate cycling, affecting cerebral phospholipid metabolism, catecholami

HY-B0389S11

D-Glucose-13C-1 Glucose-¹³C-1; D-(+)-Glucose-¹³C-1; Dextrose-¹³C-1	Endogenous Metabolite	Metabolic Disease
D-Glucose- ¹³C-1 is the ¹³C labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecules in relation to both cellular metabolic status and biotic and abiotic stress response[1].

HY-N0729S3

Linoleic acid-13C1	Endogenous Metabolite	Cardiovascular Disease Metabolic Disease
Linoleic acid- ¹³C₁ is the ¹³C labeled Linoleic acid. Linoleic acid is a common polyunsaturated (PUFA) found in plant-based oils, nuts and seeds. Linoleic acid is a part of membrane phospholipids, and functions as a structural component to maintain a certain level of membrane fluidity of the transdermal water barrier of the epidermis. Linoleic acid induces red blood cells and hemoglobin damage via oxidative mechanism [1][2].

Cat. No.	Product Name	Target	Research Area

HY-P5528

2Abz-SLGRKIQIK(Dnp)-NH2	Peptides	Others
2Abz-SLGRKIQIK(Dnp)-NH2 is a biological active peptide. (This peptide is a second complement component (C2), the physiological substrate for the proenzyme Cls, first complement component. The complement system is a central component of host defense but can also contribute to the inflammation seen in pathological conditions. The C1s protease of the C1 complex initiates the host defense pathway. This peptide employs 2Abz/Dnp FRET pair for quantitation of complement enzyme activity.)

Cat. No.	Product Name	Target	Research Area

HY-P99050

Sutimlimab	Complement System	Cardiovascular Disease Inflammation/Immunology
Sutimlimab, a first-in-class complement protein component 1, s subcomponent (C1s) inhibitor, can be used for the research of cold agglutinin disease. C1s is a serine protease which cleaves C4 and C2 to form the C3 convertase .

Species:	Human (3) Mouse (2) Rat (1) Cynomolgus (1)
Tag:	His (7)
Source:	HEK293 (5) E. coli (2)

Cat. No.	Compare	Product Name	Species	Source

HY-P700696

	*C1s/Complement component* C1s Protein, Human (HEK293, His)** Complement C1s subcomponent; C1 esterase	Human	HEK293
	C1s/Complement component C1s, a serine protease and B chain, forms C1 with C1q and C1r, initiating the classical complement pathway. Activated by C1r, C1s then activates downstream components C2 and C4, crucially driving the complement system cascade. C1s/Complement component C1s Protein, Human (HEK293, His) is the recombinant human-derived C1s/Complement component C1s protein, expressed by HEK293, with C-His labeled tag. The total length of C1s/Complement component C1s Protein, Human (HEK293, His) is 673 a.a., with molecular weight of 55-60 kDa (light chain), 32-35 kDa (heavy chain).

HY-P7692

	HABP1/C1QBP Protein, Human (His) rHuHABP1/C1QBP, His; Complement component 1 Q subcomponent-binding protein, mitochondrial; HABP1	Human	E. coli
	HABP1/C1QBP Protein, Human (His) is a recombinant human HABP1 (hyaluronan-binding protein 1)/C1QBP (complement component 1, q subcomponent binding protein) produced in HEK293 cells, with His tag. HABP1/C1QBP is a ubiquitously present glycoprotein having specific affinity towards hyaluronan (HA).

HY-P76185

	HABP1/C1QBP Protein, Mouse (His) Complement component 1 Q subcomponent-binding protein, mitochondrial; HABP1	Mouse	E. coli
	HABP1/C1QBP Protein, part of the MAM33 family, is associated with a distinct protein family known for unique characteristics and functions. In the MAM33 family, HABP1 likely plays a significant role in associated cellular processes, though specific functions need exploration. Investigating HABP1's functions and implications within the broader MAM33 family will enhance understanding of its unique properties and potential roles in cellular processes, offering insights into its significance within this protein family. HABP1/C1QBP Protein, Mouse (His) is the recombinant mouse-derived HABP1/C1QBP protein, expressed by E. coli, with N-His labeled tag. The total length of HABP1/C1QBP Protein, Mouse (His) is 208 a.a., with molecular weight of ~32 KDa.

HY-P75373

	CD93/C1qR1 Protein, Mouse (HEK293, His) Complement component C1q Receptor; CD93; C1qRp; Ly-68; C1qr1	Mouse	HEK293
	The CD93/C1qR1 protein, as a receptor or part of a larger complex, is a multifunctional mediator in immune recognition and cellular interactions. It has been shown to play a role in coordinating immune responses as a binding site for C1q, mannose-binding lectin (MBL2), and pulmonary surfactant protein A (SPA). CD93/C1qR1 Protein, Mouse (HEK293, His) is the recombinant mouse-derived CD93/C1qR1 protein, expressed by HEK293 , with C-10*His labeled tag. The total length of CD93/C1qR1 Protein, Mouse (HEK293, His) is 550 a.a., with molecular weight of ~60.9 kDa.

HY-P75661

	CD93/C1qR1 Protein, Rat (HEK293, His) Complement component C1q Receptor; CD93; C1qRp; Ly-68; C1qr1	Rat	HEK293
	The CD93/C1qR1 protein is a receptor or component of a larger complex that is critical in immune recognition and response. It acts as a receptor for C1q, mannose-binding lectin (MBL2), and pulmonary surfactant protein A (SPA), suggesting a role in interactions with multiple immune components. CD93/C1qR1 Protein, Rat (HEK293, His) is the recombinant rat-derived CD93/C1qR1 protein, expressed by HEK293 , with C-His labeled tag. The total length of CD93/C1qR1 Protein, Rat (HEK293, His) is 571 a.a., with molecular weight of 75-90 kDa.

HY-P7691

	CD93/C1qR1 Protein, Human (HEK293, His) 1 Publications Verification rHuCD93, His; Complement component C1q Receptor; Matrix-Remodeling-Associated Protein 4CD93; CD93	Human	HEK293
	CD93/C1qR1 Protein, Human (HEK293, His) is a recombinant human CD93 produced in HEK293 cells, with His tag. CD93 is a type 1 transmembrane glycoprotein.

HY-P700464

	CD93/C1qR1 Protein, Macaca fascicularis (HEK293, His) rHuCD93, His; Complement component C1q Receptor; Matrix-Remodeling-Associated Protein 4CD93; CD93	Cynomolgus	HEK293
	CD93/C1qR1 Protein lacks conserved residue(s) crucial for feature annotation propagation. CD93/C1qR1 Protein, Macaca fascicularis (HEK293, His) is the recombinant cynomolgus-derived CD93/C1qR1 protein, expressed by HEK293 , with C-10*His labeled tag. The total length of CD93/C1qR1 Protein, Macaca fascicularis (HEK293, His) is 558 a.a., with molecular weight of 60.2 kDa.


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Cat. No.	Product Name	Chemical Structure

HY-B0158S2

Cytidine-13C-1
Cytidine- ¹³C-1 is the ¹³C labeled Cytidine. Cytidine is a pyrimidine nucleoside and acts as a component of RNA. Cytidine is a precursor of uridine. Cytidine controls neuronal-glial glutamate cycling, affecting cerebral phospholipid metabolism, catecholami

HY-B0389S11

D-Glucose-13C-1
D-Glucose- ¹³C-1 is the ¹³C labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecules in relation to both cellular metabolic status and biotic and abiotic stress response[1].

HY-N0729S3

Linoleic acid-13C1
Linoleic acid- ¹³C₁ is the ¹³C labeled Linoleic acid. Linoleic acid is a common polyunsaturated (PUFA) found in plant-based oils, nuts and seeds. Linoleic acid is a part of membrane phospholipids, and functions as a structural component to maintain a certain level of membrane fluidity of the transdermal water barrier of the epidermis. Linoleic acid induces red blood cells and hemoglobin damage via oxidative mechanism [1][2].

Linoleic acid-13C1

Linoleic acid- ¹³C₁ is the ¹³C labeled Linoleic acid. Linoleic acid is a common polyunsaturated (PUFA) found in plant-based oils, nuts and seeds. Linoleic acid is a part of membrane phospholipids, and functions as a structural component to maintain a certain level of membrane fluidity of the transdermal water barrier of the epidermis. Linoleic acid induces red blood cells and hemoglobin damage via oxidative mechanism [1][2].

Cat. No.	Product Name	Application	Reactivity

HY-P81468

C1QA Antibody (YA1213)

C1qa; Complement C1q subcomponent subunit A; Complement component 1 q subcomponent A chain; Complement component 1 q subcomponent alpha polypeptide
IHC-P Human
HY-P81889

C1QB Antibody (YA1634)

C1qb; Complement component 1 q subcomponent B chain
WB, IHC-P, ICC/IF Human

HY-P82566

GC1q R Antibody (YA2311) C1QBP; GC1QBP; HABP1; SF2P32; Complement component 1 Q subcomponent-binding protein; mitochondrial; GC1q-R protein; Glycoprotein gC1qBP; C1qBP; Hyaluronan-binding protein 1; Mitochondrial matrix protein p32; p33	WB, IP	Human, Mouse, Rat

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